ABSTRACT
Objective To explore the clinical application value of coronary angiography (CAG) combined with fractional flow re-serve(FFR) in percutaneous coronary intervention treatment of coronary artery disease (CAD) .Methods 82 cases of CAD(147 le-sions) with single hemadostenosis at least 70% -90% were randomized into the observation group and the control group .The ob-servation group(40 cases ,72 lesions) was performed the myocardial FFR detection by the pressure guide wire and the drug-eluting stents(DES) were placed in the lesions only if FFR ≤0 .80 .The patients with postoperative FFR ≤0 .80 were given the in-stent post-balloon dilatation .The control group(42 cases ,75 lesions) underwent the percutaneous coronary intervention(PCI) for conduc-ting the routine DES implantation .The general condition ,risk factors(hypertension ,diabetese ,hyperlipidemia ,smoking ,etc .) ,num-ber of lesions ,implanted stents ,hospitalization cost ,occurrence rate of major adverse cardiac events (MACE) after postoperative 6 months and the angina recurrence rate were compared between the two groups .Results The number of used stents per patient and the hospitalization cost in the observation group were significantly lower than those in the control group [(0 .88 ± 0 .88) vs .(1 .81 ± 0 .83) ,(47 200 ± 2 3000)Yuan vs .(60 000 ± 2 4100)Yuan P0 .05) .Conclusion CAG combined with FFR detection can significantly reduce the number of stents and the hospitalization cost without increasing the occur-rence rates of MACE and angina within postoperative 6 months in CAD patients .
ABSTRACT
OBJECTIVE:To probe into the perioperative prophylactic use of antibiotics in township hospitals. MENTHODS:A total of 100 perioperative medical records in 10 township hospitals were randomly sampled from Jan. to Jun. in 2008 for retrospective analysis of the perioperative prophylactic use of antibiotics in respect of the drug kinds,drug application frequency,medication duration and drug combinations,etc. RESULTS:All of the patients received prophylactic antibiotics and the use of antibiotics was characterized by high starting point,widespread drug combination,lacking of consciousness of preoperative use of antibiotic in the initial medication time and prolonged medication duration. CONCLUSION:In order to standardize perioperative use of antibiotics and decrease incidence of adverse drug reactions and drug resistance,it is important to strengthen the training and supervision on the rational use of antibiotics among clinicians and pharmacists in township hospitals.